Is Opioid Tolerance Permanent?
- Posted By:
- 'Kenneth' on
- 1 Answer
- Pramod Kerkar, MD, FFARCSI, DA
Opioid tolerance is not permanent but often sustained for one particular opioid if you continue taking that opioid. The tolerances causes need to increase dosage frequently to achieve adequate pain relief. Frequent increase in dosage causes tolerance and resistance to opioid for therapeutic effects and pain relief. Opioid tolerance is prevented by switching opioids to different types and adding long acting opioids to short acting opioids. In few cases opioid holidays for few weeks to months eliminates the opioid tolerance.