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Strep throat is treated by antibiotics. As soon as antibiotic course is started, the symptoms of strep throat start to go away within 24 hours of the first dose of antibiotics. Within 5 days of the antibiotic course, strep throat should be treated. So, with treatment, strep throat should not last for more than 2 to 5 days. However, if strep throat lasts for longer, there are chances that the condition is caused by some other disease or the infection has spread to other parts of the body.