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Any type of weather changes tends to cause an eczema flare-up in many people. Which weather makes it worse depends on the individual. On a general level, though, hot, cold, dry, and humid, weathers are known to wreak havoc on eczema flare-ups. Weather can affect your eczema directly and indirectly. A warm, windy day can cause pollen to blow into the air and your skin gets exposed to this, thus leading to an itchy flare-up. Often people find that the hot weather triggers prickly heat and leads to a frenzy of scratching.