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Liver spots generally appear as flat or circular shaped and discolored spots at the back of the hands, arms and the face and in other areas which have a frequent exposure to direct sunlight. The discoloration can range from light tan to deep brown in color. Although, liver spots on face, hands, and skin can be treated in a number of ways, either through the use of over-the-counter medications or following home remedies, protecting the skin from the harmful ultraviolet rays of the sun and using of sunscreen lotions are the best options.