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There are a lot of factors which are at play when it comes to sleeping comfortably with scoliosis. Sleeping is something which most individuals with scoliosis are concerned about. This is because it is very difficult to find a comfortable position to sleep in cases of scoliosis. it is not only the positions of sleep that makes a difference but the selection of mattress and use of pillows also make a huge difference when deciding how should one sleep with scoliosis.