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A chest infection affects the lungs or your airways. An infection of the lungs or large airways is known as a chest infection. If the infection affects the larger airways, it is known as bronchitis, and if it affects the smaller air sacs, it is known as pneumonia. Caused by a virus, this type of chest infection (Bronchitis) usually lasts for seven to ten days, and Pneumonia, which is another type of chest infection can last for anywhere between two to three weeks. Some of the best antibiotics for chest infections are amoxicillin, cefuroxime, Clarithromycin, and Cephalexin.