What Is The Treatment For Nil Sperm Count?

Nil sperm count or zero sperm count characterizes a condition known as azoospermia. It is evident in a man’s ejaculate, whereby after ejaculation, the semen contains no sperms. The absence of sperms in the ejaculate does not necessarily imply that one is not producing the sperms, or rather they are infertile. The underlying condition could be obstructive azoospermia, which implies that there is an obstruction in the passageway between the testes and ejaculatory duct. Even in cases of non-obstructive azoospermia, when the problem could be sperm production, after medical intervention there could be small amounts of sperms in the testicles which can be harvested.

What Is The Treatment For Nil Sperm Count?

What Is The Treatment For Nil Sperm Count?

Cases of obstructive azoospermia/nil sperm count can be treated efficiently except for any congenital defects such as the absence of the vas deferens. Possible treatment options include microsurgery and endoscopic reconstruction. Patients with obstructive azoospermia can also choose treatment with assisted reproduction technology which involves extraction of sperms from the testes or epididymis to enhance conception. Surgery can be employed for patients with an obstructed vas deferens, where the obstruction can easily be removed and repair done on the damaged area.

For patients with non-obstructive azoospermia/nil sperm count, they can be treated using medical interventions which will stimulate ejaculation of semen with sperms. In cases of patients with Kallman syndrome or varicocele, the underlying causative problems can be reversed, thus enhancing sperm ejaculation. Most individuals with non-obstructive azoospermia have about 50-60% usable testicular sperms, which makes it difficult to fully achieve reversed azoospermia after treatment. Therefore, for most of these individuals, the most effective mode of treatment is sperm retrieval, which can then be used in assisted reproduction technology.

If the underlying cause of nil sperm count (azoospermia) is infection, the patient can be subjected to antibiotic therapy until the infection is gone. However, treatment of infections does not entirely cure the condition of zero sperm count. So, further treatment can be offered to enhance sperm production, provided that the condition can be reversed. For patients with sexual intercourse problems, they are treated using medication therapy which aids in improving their fertility and combating the underlying problem. Hormone treatment is ideal for those who have low or high levels of hormones which implicate sperm ejaculation. The nil sperm count condition can be reversed either through hormone medications or hormone replacement in the body.

What Next If Medical Treatments Fail?

The probability of medical treatment options for nil sperm count failing are low, but in case it does happen what can you do? First things first, you can change any lifestyle habits which can induce infertility and interfere with sperm production such as alcohol and smoking. In addition to that, if you are obese, shed off some weight and ensure that you eat a well-balanced and nutritional whole foods diet. You could also take specific herbs which are known to help with hormone balance and sperm production such as maca root, American ginseng root, Tribulus, saw palmetto berries and Cordyceps mushroom to name a few.

What Causes Nil Sperm Count?

The two major causes of nil sperm count are associated with sperm production or delivery of sperms. In the former scenario, the condition is referred to as non-obstructive azoospermia whereas, in the latter scenario, the condition is referred to as obstructive azoospermia. Obstructive azoospermia can be caused by; vasectomy (where the sperm ducts are removed), infections of the testicles, prostate, and epididymis, surgical complications of urogenital organs and congenital disorders such as the absence of the vas deferens. Non-obstructive azoospermia can be attributed to genetic composition anomalies, hypospermatogenesis, testicular cancer, Kallman syndrome, varicocele, maturity arrest, chemotherapy and radiation therapy as well as Sertoli-cell only (SCO) syndrome.


It is important that you take your prescribed medications and complete the dosage as required. Also, eat a nutritious diet which will enhance spermatogenesis and boost your overall well-being. Nil sperm count (azoospermia) is a treatable condition as long as the underlying cause can be reversed. Otherwise, sperms can be harvested from the testicles or epididymis, and used for assisted reproduction, for patients who want to father children. Azoospermia is usually treated using both surgical and medical interventions depending on the extent of the condition and the damage caused. Congenital related azoospermia cannot be effectively treated. In case of any side effects from the applied treatment option, contact a physician as soon as possible.

Team PainAssist
Team PainAssist
Written, Edited or Reviewed By: Team PainAssist, Pain Assist Inc. This article does not provide medical advice. See disclaimer
Last Modified On:December 27, 2018

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