Olfactory neuroblastoma is a very rare malignant tumor that develops in the upper part of the nasal cavity. Babies and young children are the most affected by this condition. Neuroblastoma usually develops from the specialized nerve cells. It seldom shows bilateral proptosis and blindness.
A total of 876 cases of olfactory neuroblastoma reported from 1975 to 2015. Most patients were white and most of them were male than females. Most of the cases have a high risk of disease relapse. Also, about 15 percent of these patients don’t respond to initial treatment.
Can Olfactory Neuroblastoma Go Away On Its Own?
Some kinds of neuroblastoma resolve on their own, whereas others may necessitate several treatments. Your child’s neuroblastoma treatment choices will vary in a multitude of aspects. Physicians give chemo in phases, which comprise of therapy on limited time in a sequence, followed by time off to let the body time to recuperate. The phases are usually repeated every 21 days or 28 days. The overall duration of therapy varies on which risk group the infant is in – higher-risk groups usually require longer treatment
Neuroblastoma groups occur from the adrenal medulla or paraspinal spots where the sympathetic nervous system nerve is situated. Neuroblastoma tumor units can propagate (metastasize) rapidly to more regions of the body. The condition arises when normal fetal neuroblasts do not turn mature nerve cells or adrenal medulla cells. As an alternative, they continue to develop and split up. Neuroblasts may not have matured entirely in infants by the time they are born.1,2
One of the extremely widespread symptoms of neuroblastoma is a significant tumor or bulging in the baby’s stomach. The infant might not feel appetizing and hates food. In the majority of instances, neuroblastoma cells make adequate catecholamines to be identified by plasma or urine analysis. A urinalysis (urine analysis) may also be performed to help examine kidney function. Olfactory neuroblastoma has one of the shortest survival figures of all childhood tumors, with only 65% of patients stay alive to five years. This is also one of the few types of cancer for which survival varies substantially between the genders – boys have a harsher stance than girls.3
What Are The Natural Remedies For Olfactory Neuroblastoma?
Most patients often wonder if there are any natural remedies to manage this condition and improve the symptoms. However, there are no standard treatments for recurrent neuroblastomas and the treatment typically includes chemotherapy and radio surgical treatment. If you’re detected with olfactory neuroblastoma, your health care specialist team, including neurologists and neurosurgeons, will devise a plan for you to determine the best possible treatment plan.
Often, a sequence of radiation therapy, chemotherapy and surgery are suggested.
Chemotherapy: A patient with olfactory neuroblastoma had a wide connection of the nasopharynx, sinuses and orbit, and cervical metastasis. Following surgical biopsy and removal of metastatic illness, the patient is typically treated with chemotherapy for a durable of three cycles. Chemotherapy is followed by concurrent chemoradiation and this treatment generally produces positive results.
Stereotactic Radio Surgical Treatment Of Olfactory Neuroblastoma – This is one of the most effective treatments of olfactory neuroblastoma and a total of more than 30 locally recurrent cancers were treated with stereotactic radiosurgery. Stereotactic computed tomography (CT) was also used in discriminatory instances at the decision of the treating physicians.
Craniofacial resection is the best conventional treatment for core disorder, either in combination with preoperative radiation and chemotherapy, or selective postoperative radiation and adjuvant chemotherapy dependent on stages. Best survival outcomes were found for treatment with radiotherapy.4,5
- Olfactory Neuroblastoma (Esthesioneuroblastoma)- UPMC Life Changing Medicine https://www.upmc.com/services/neurosurgery/brain/conditions/brain-tumors/olfactory-neuroblastoma
- Side effects of surgery for nasal cavity and paranasal sinus cancer https://www.cancer.ca/en/cancer-information/cancer-type/nasal-paranasal/treatment/surgery/potential-side-effects/?region=qc
- Can olfactory neuroblastoma Go Away On Its Own https://www.nhs.uk/conditions/neuroblastoma/
- Olfactory Neuroblastoma (Esthesioneuroblastoma) – Aurora Health care https://www.aurorahealthcare.org/services/neuroscience/brain-skull-base-care/brain-tumor/olfactory-neuroblastoma
- Chemo-radiotherapy for olfactory neuroblastoma: cases report and literature review http://tro.amegroups.com/article/view/5219/html
- What is Esthesioneuroblastoma or Olfactory Neuroblastoma: Causes, Symptoms, Treatment, Recovery, Prognosis, Staging
- Is Olfactory Neuroblastoma Hereditary?