Half of the world population and almost 60% of Indians are serologically naive and at risk of acquiring parvovirus B19 infection.(1)
Numerous reports according to data studies have shown B19 infections can play a significant role in multiorgan diseases.(1)
Can Parvovirus B19 Infection Go Away On Its Own?
In healthy individuals, the infection can be short-lived and resolve on its own in due time without any clinical manifestations. The immune system of the body is enough to fight the illness resulting in the virus going away on its own. Complications can be seen in immunocompromised patients and underlying hemolytic disorders. It is, therefore, necessary to diagnose the condition beforehand, especially in people with underlying blood disorders that can lead to chronic infections. Avoiding infections with the b19 virus also become necessary to further prevent complications. Care should be taken during pregnancy as the fetus can be severely damaged, especially during the second semester if infected with the virus. A medical checkup and follow-up for pregnant women will result in fewer fetal fatalities.(2)
The majority of the parvovirus b19 infections are clinically asymptomatic. The detection of b19 virus-specific antibodies shows that an individual had been affected by the virus. When IgM antibodies are present, they indicate a recent infection with the virus. However, circulating b19 virus antibodies can be detected in the serum several months later with the PCR or nucleic acid amplification techniques, therefore making it difficult to diagnose the clinical condition.(3)
The diseases caused by the parvovirus b19 include:
- Erythema infectiosum or Morbus Quintus or fifth disease in children.
- Arthritis, arthralgia can be seen in 8% of the previously infected children and 80% of the adults.
- Aplastic crisis in individuals who have chronic hemolytic disorders
- Chronic anemia can be seen in immunosuppressed patients and patients with blood disorders such as leukemia.
- Congenital anemia when a virus transmitted during pregnancy
- Fetal anemia and hydrops fetalis.
Serious diseases can occur in an individual in advanced age as the body is unable to fight the virus.(3)
What Are The Natural Remedies For Parvovirus B19?
There are no remedies to prevent the infection of parvovirus b19; however, measures to relieve the symptoms can be taken. Certain homeopaths also suggest the use of APIS, belladonna, chamomilla, calendula, sulfur, Urtica urens, etc. to manage the symptoms of the disease. These substances are high in anti-inflammatory substances relieving symptoms of sore throat, cold, fever, and swelling. A person acquires lifetime immunity against the parvovirus b19 after being infected with the disease. So, further outbreaks will not lead to diseases in healthy individuals as the antibodies are pre-formed in the body.
When going for natural remedies a good healthy lifestyle along with some exercise helps a person build good immunity and strengthens the respiratory system to fight the disease naturally. Also, staying at home during an outbreak will prevent further infection with the virus.(2)
Transmission And Diagnosis Of Virus
Transmission of the b19 virus mostly takes place through respiratory droplets, transfusion of b19 viremic blood or blood components, or transplacentally from mother to fetus during pregnancy. Droplet infection is the most common mode of transmission of diseases where the multiplication of the virus takes place in the throat followed by viremia resulting in high titers of B19 virus. The laboratory diagnosis is made based on the detection of immunoglobulin G (IgM) antibodies specific to the B19 virus with ELISA or B19V DNA in the serum or bone marrow. When there are infected tissues present the virus can be detected by in situ hybridization or other common methods being PCR or real-time PCR specifically. Other modalities of diagnosis include electron microscopy to demonstrate B19V virions in serum as high titers of virus can be found in acute infections. In some cases, cytomorphology of bone marrow aspirate can also be done to reach the presumptive diagnosis of b19 infection.(1)
- Can Parvovirus B19 Infection Cause Lupus & Does It Cause Joint Pain?
- Can Parvovirus B19 Infection Cause Rheumatoid Arthritis & Is It An Autoimmune Disease?
- What Is The Prognosis For Parvovirus B19 Infection & Lifestyle Changes For It?
- How Did I Get Parvovirus B19 Infection & What Is The Best Treatment For It?
- Who Is At Risk For Parvovirus B19 Infection & Is There A Blood Test For It?