Humira or adalimumab can reduce white blood cells in your body as well as your blood clotting ability. Your blood should be checked regularly. Prevent being close to ailing people and those with infections. Also avoid tasks that put you in danger of bleeding injuries. During humira or adalimumab therapy, deadly and severe infection can appear.
Notify your doctor immediately if you have any symptom of infections.
Contact your doctor immediately if you have signs like decrease in weight, fever, upper stomach pain, night sweats, dark urine, jaundice, easy bleeding and bruising or feeling full after eating minute quantity of meals.
How Effective is Humira?
Humira or adalimumab effectively minimizes the properties of a substance that causes inflammation in the body.
Humira or adalimumab is prescribed in effective treatment of juvenile idiopathic, rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, ankylosing spondylitis and severe skin illness known as hidradenitis suppurativa. This medicine humira or adalimumab is also effectively utilized in treatment of ulcerative colitis or Crohn’s disease in cases where other medications have been used without success.
Certain patients can develop unusual fast budding type of cancer known as lymphoma. This state is deadly and it affects the spleen, bone marrow and liver. This medicine humira or adalimumab can also reduce the white blood cells and the ability of your blood clotting. During humira therapy, deadly and severe infection can appear.
Before Using Humira
People who are allergic to adalimumab or those who have active infections should never use Humira.
Certain patients can develop unusual fast budding type of cancer known as lymphoma. This state is deadly and it affects the spleen, bone marrow and liver. This most common in young adults and teenagers on humira treatment as well as other similar drugs used to treat ulcerative colitis or Crohn’s illness. However, patients with autoimmune problems are at increased risk of lymphoma.
Before you start your humira or adalimumab dosage, the doctor can carry out some tests to check if you have tuberculosis or some other infections.
To be safe with humira or adalimumab inform your physician if you have:
- Current or severe infections
- Precedent or active cancer
- Congestive heart failure
- A record oh having hepatitis b
- If you are allergic to latex rubber
- If you recently visited a tuberculosis prone area or if your family has history of tuberculosis,
- Tingling or numbness, or a nerve muscle problem like Guillain-Barre syndrome or multiple sclerosis.
Some infections are rampant in some parts of the world. Inform your physician of where you reside and where you have planned to visit during your treatment.
Humira or adalimumab is not likely to hurt unborn baby. Notify your doctor if you are pregnant or planning to become pregnant while using humira.
It is not established whether humira or adalimumab mixes with mothers’ milk or if it can hurt a nursing child. Inform your doctor if you are nursing your baby.
Humira or adalimumab medicine should not be administered to children of below 6 years when treating Crohn’s disease. Children who are taking humira or adalimumab must be current on every childhood immunizations prior to starting treatment.
Taking humira or adalimumab will escalate your danger of having some forms of cancer like lymphoma (lymph nodes cancer) or melanoma (tumor that affects the skin). It may also lead to autoimmune problems such as lupus-like-syndrome. Inform your physician of your exact risk.
What is the Suggested Dose of Humira?
General Adult Dosage of Humira or Adalimumab for Treating Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis:
Inject humira or adalimumab 40 milligrams each week. Patients who are not using concomitant methotrexate, the dosage gap can be enlarged to 40 milligrams each week.
Analgesics, salicylates, methotrexate, nonsteroidal anti-inflammatory medicines, glucocorticoids, or other illness modifying agents can be administered concurrently.
General Adult Dosage of Humira or Adalimumab for treating Crohn’s Disease – Severe, continuation and also for Ulcerative Colitis:
First dosage: Inject 160 milligrams of humira or adalimumab under the skin on day 1. The first dosage can be issued as 4 injections on the first day or as 2 injections each day for 2 successive days.
Week 2: Inject 80 milligrams under the skin on day 15.
Maintenance dosage: Commencing week 4, inject 40 milligrams each week.
Immunomodulatory, corticosteroids and/ or Aminosalicylates agents can be given in the course of adalimumab therapy.
Using of Humira to treat crohn’s disease for more than 1 year has not been researched in clinical studies.
General Adult Dosage of Humira or Adalimumab for Treating Plaque Psoriasis:
Initial dosage: Inject 80 milligrams under the skin.
Maintenance dosage: Inject 40 milligrams of humira or adalimumab under the skin each week, one week after the initial dosage.
Pediatric Dosage of Humira or Adalimumab for Treating Juvenile Idiopathic Arthritis:
For children between 4 to 17 years:
Inadequate information is available for humira or adalimumab therapy in children with less than 15 kg body weight.
For children with 15 to 30 kg body mass: Inject 20 milligrams each week.
For children with more than 30 kg body weight: inject 40 milligrams each week.
Glucocorticoids, Methotrexate, NSAIDs, analgesics or salicylates can be given concurrently with humira or adalimumab.
What are the Side Effects of Humira?
Get prompt health assistance if you have any symptoms of allergy to humira or adalimumab: such as hives or swelling of your lips, breathing difficulties, tongue, face, and throat.
Stop using humira or adalimumab and contact your doctor immediately when you have these signs of lymphoma:
- Felling satisfied after eating little amounts of food,
- Fatigue, fever, night sweats, weight loss,
- Upper stomach pain that scatters to your shoulders,
- Pale skin, easy bleeding or bruising, fast heartbeats, feeling to faint,
- Signs of liver problems such as itching, upper stomach pain, nausea, dark urine lack of appetite, jaundice, clay colored stools.
Contact your doctor urgently if you have the below mentioned severe side effects of humira or adalimumab:
- Vision problems,
- Short breaths and swelling feet or ankles,
- Tingling, numbness, pricking or weak feeling,
- Easy bleeding and bruising, pale skin,
- New or escalating raised and silvery flaking of your skin (psoriasis),
- Symptoms of tuberculosis such as weight loss, fever and continuing coughs,
- Symptoms of infections such as vomiting, sore throat, chills, fever, flu signs, diarrhea, burning or pain when urinating.
Elderly patients are more likely to have infections when using humira or adalimumab.
Common side effects of humira or adalimumab can include:
- Signs of flu like sinus pain, sore throat, sneezing, stuffy nose are all side effects of humira or adalimumab.
- Itching, bruising, redness or swelling of the injected spot.