How Safe Is It To Take Aloe Vera Juice With Other Medications?

The Aloe Vera plant is recognized as a juicy plant species from Aloe. This plant grows in abundant quantities in tropical climates and people use the juice of this plant for ages. Most of the people aren’t sure whether or not they should take Aloe Vera juice along with other medications. Generally, if you consume Aloe juice it will not pose any vital health risks. However, sometimes, natural substances too pose danger to your health; so, if you take Aloe vera besides other medications then it can result in negative effects. This is why; you must have a consultation with your physician prior to drinking the juice of Aloe Vera. This is of utmost importance when you are drinking this juice in huge quantities for getting some kind of medicinal impact.

How Safe Is It To Take Aloe Vera Juice With Other Medications?

How Safe is it to take Aloe Vera Juice with Other Medications?

According to the Beth Israel Deaconess Medical Centre, if you consume Aloe juice then it can lessen the levels of your blood sugar. However, this optimistic effect can turn negative if you take it along with insulin or other medications meant for controlling diabetes. The combination of Aloe juice and these medications can cause hypoglycemia. When you consume a compound having a similar effect like a medicine you are needed to lessen the dosage of the compound to compensate for these impacts. Now, if you have an interest in making use of Aloe for treating diabetes, then have a talk with your doctor who will monitor your treatment before determining whether or not you need such a transformation.

Medications With Which Aloe Vera Juice Should Not Be Taken

Avoid Taking Aloe Vera Juice When Taking Medications Which Drastically Lowers the Levels of Potassium:

Potassium has much vital significance in your body and so, you must maintain its proper levels. There are some medicines, like thiazide diuretics. This medicine is used for treating hypertension and heart medicine digoxin has the capability to lessen the levels of potassium in your body. Aloe Vera contains laxative properties and this is why a prolonged use of this compound can lessen the levels of potassium and it can dangerously create low levels.

Impact of Aloe Vera Juice on Medicines that are Metabolized by the Enzyme CYP2D6:

The human body comprises of various enzymes which metabolize substances, like drugs or herbs which come via your body. According to The MSKCC (Memorial Sloan-Kettering Cancer Center), Aloe Vera can constrain the effects of this enzyme and this can result in increased concentrations of the medicine in the body, thus resulting in a danger of experiencing serious side effects. Tricyclic antidepressants plus other drugs are used for addressing mental plus emotional disorders and they are some of the drugs which need this enzyme.

Impact of Aloe Vera Juice on Medicines that are Metabolized by the Enzyme CYP3A4:

According to the reports of the MSKCC, Aloe vera is an important factor which hinders the actions of the CYP3A4 enzyme and based on the magazine, “Pharmacy Times”, nearly 50 percent of all medicines present in the market get broken down by this particular enzyme. Aloe juice certainly affects these enzymes but doesn’t suggest a reaction automatically, but there is always a probability. Therefore, if you consume any type of medication you must have a consultation with your physician beforehand.

Aloe Vera Juice and HIV Medicines:

There are some supplements which make some specific drugs that are used for treating HIV infection lesser effective or augment the danger of side effects. So, if you are on HIV medicines, then you should keep yourself away from Aloe Vera, St. John’ Wort, garlic, and kava.

Blood Pressure and Heart Medicines and Aloe Vera Juice:

There are many dietary supplements and drugs that pose severe risks when combined with antihypertensive and cardiac medications. This precaution applies to every kind of beta-blocker, calcium channel blockers, nitrate medication, ACE or angiotensin-converting enzyme, or digitalis drugs, like Sigmaxin and Lanoxin. You can come across serious side effects when you combine these compounds with Aloe Vera juice.

Medicines That Are Safe To Be Taken With Aloe Vera Juice

The medicines or natural components with which Aloe Vera juice does not interact includes:

  • Castor oil
  • Aspirin or Aspirin low strength
  • Ginger root or ginger
  • Benadryl or diphenhydramine
  • CoQ10 or ubiquinone
  • Ginkgo Biloba
  • Fish Oil
  • L-Carnitine or Levocarnitine
  • Synthroid or Levothyroxine
  • Tylenol or Acetaminophen
  • Chondroitin & Glucosamine
  • Lidocaine
  • Honey
  • Omeprazole
  • Miralax or Polyethylene Glycol 3350
  • Omega -3
  • Probiotic formula
  • Omeprazole
  • Vitamin B12 or cyanocobalamin
  • Synthroid
  • Vitamin B6 or pyridoxine
  • Vitamin C or ascorbic acid
  • Vitamin E
  • Vitamin D3 or cholecalciferol
  • Zyrtec or cetirizine
  • Zinc or zinc sulphate
  • Xanax or alprazolam.


Besides interactions with other medications, taking Aloe juice for a long period of time can cause skin allergies, such as widespread inflammation and hive and it can also cause redness in your eyelids plus other effects on your skin, like dryness, hardening, splitting, plus the growth of purple spots. This is why it is extremely important to have a talk with your physician regarding the use of Aloe Vera juice alone or with other medications to keep the risks of side effects at bay.

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Team PainAssist
Team PainAssist
Written, Edited or Reviewed By: Team PainAssist, Pain Assist Inc. This article does not provide medical advice. See disclaimer
Last Modified On:March 18, 2019

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