Monoclonal gammopathy of undetermined significance (MGUS) is a blood disorder characterized by the presence of abnormal proteins in the blood known as monoclonal protein or M protein. MGUS as such does not produce any symptoms, but the untreated disorder can result in fatal blood cancers. These abnormal proteins are produced by the white blood cell (plasma cells) in bone marrow.
People who are diagnosed with MGUS should be monitored regularly to avoid the progression of the disease. Regular checkup should be done to avoid multiple myeloma which significantly decreases the life expectancy of the individuals. It is now established that multiple myeloma is always preceded by monoclonal gammopathy of undetermined significance. Previously monoclonal gammopathy of undetermined significance did not have any significance for the progression of the disease. It is more significant in African-American populations than the older white general population.
What To Eat & Avoid When You Have MGUS Or Monoclonal Gammopathy Of Undetermined Significance?
Foods To Eat In Monoclonal Gammopathy Of Undetermined Significance.
Curcumin is the miracle spice with scientific evidence which inhibits or stops the multiplication of cancerous cells in the body. This yellow pigment of turmeric is curcumin. It is being used traditionally as a household item. In vitro studies indicate higher the amount of curcumin higher is the slowing of progression g the disease. Clinical trials have also been performed and many patients have responded to curcumin treatment. The number of paraproteins in the blood was taken as a measure to analyze the progression of the disease. Patients treated with curcumin had decreased paraproteins levels in the blood. It has helped in controlling multiple myeloma in the initial stages of the disease. It is recommended to take a quarter spoon of turmeric per day.
Shallots, garlic, soy foods, and green tea reduce the risk of developing monoclonal gammopathy of undetermined significance to multiple myeloma.
The doctor may advise you to have a low fiber diet BRAT diet (bananas, rice, applesauce, and toast) to add fiber and drink plenty of water to keep yourself hydrated. If you find it difficult to swallow eat pudding or mashed potatoes, this will not be spicy to irritate your tongue and mouth.
The cancer cells will find their way to bone marrow blocking the release of healthy red blood cells resulting in anemia. Eating of beans and dark green vegetables can help in overcoming anemia.
Your doctor will advise you the supplements to fill the nutritional gap; you may be prescribed food supplements such as iron, vitamin D and fish oil. Healthy eating habits will help you in fighting not only monoclonal gammopathy of undetermined significance and other diseases but will make you stronger to live a happy and versatile life.
Foods To Avoid In Monoclonal Gammopathy Of Undetermined Significance.
Meat. meat-eaters have been associated with an increased risk of developing blood cancers. There can be cancer-causing viruses which get transferred from the meat of the animals into human upon consumption. Cattle and chicken both increases the risk of monoclonal gammopathy of undetermined significance and hence multiple myeloma. Avoid eating raw meat, runny eggs, sushi, and unpasteurized drinks.
Diet Soda. There are studies which indicate diet soda containing aspartame increases the risk of blood cancers.
Potatoes. Potato is one of the favorite veggies of all, but French fries and potato chips are not good for health and should not be consumed even in pickle form. These increase the risk of multiple myeloma.
Pickled vegetables have a greater tendency of putting you at risk of developing multiple myeloma.
Conclusion
Include lots of fruits and vegetables in the diet which are rich in antioxidants. Include turmeric powder in the diet which helps in fighting against the cancer cells. It is particularly useful when the immune system is compromised. Avoid eating raw foods especially raw meat as it increases the risk of monoclonal gammopathy of undetermined significance. Eat cooked vegetables and fruits to reduce the risk of infections. Right diet will help you in fighting the symptoms of the disease and also controlling the progression.
- Mayo Clinic Staff. (2021). Monoclonal Gammopathy of Undetermined Significance (MGUS). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/monoclonal-gammopathy-of-undetermined-significance/symptoms-causes/syc-20352369
- Leleu, X., Roccaro, A. M., Moreau, A. S., Dupire, S., Robu, D., & Ziober, A., et al. (2020). Curcumin improves the therapeutic efficacy of L3MBTL1 inhibitor SGC 0946 in multiple myeloma through NRF-2 mediated autophagy. Haematologica, 105(1), 241-251. doi: 10.3324/haematol.2018.206573
- Carr, A. C., & Frei, B. (1999). Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. American Journal of Clinical Nutrition, 69(6), 1086-1107. doi: 10.1093/ajcn/69.6.1086
- The American Journal of Clinical Nutrition. (2003). Folate, vitamin C, and vitamin E intake and plasma homocysteine levels in men with chronic obstructive pulmonary disease. The American Journal of Clinical Nutrition, 77(2), 300-307. doi: 10.1093/ajcn/77.2.300
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