In this section of the article you will find out the treatment for myelodysplastic syndromes or MDS which includes chemotherapy, immunotherapy, stem cell/bone marrow transplant for myelodysplastic syndromes or MDS.

Myelodysplastic Syndromes Treatments

Treatment for Myelodysplastic Syndromes or MDS

The goal of the treatment for myelodysplastic syndromes or MDS is to reduce the advancement of the disease and manage the signs and symptoms such as anemia, reducing infections, managing fatigue etc. Proper treatment plays an important role in lowering the speed of the disease and improves the life style of the patients by many notches.

Doctors use a combination of treatment to alleviate the suffering of the myelodysplastic syndromes or MDS patients. The entire health care team collaborates with each other to provide better treatment options. For instances, nurses and paramedical staff combine together to deliver sterling results to the victims of myelodysplastic syndromes or MDS. It is important to consult the dietician before proceeding ahead with the treatment process.

Doctors focus on remission and try to increase the blood count levels. They select the treatment process for myelodysplastic syndromes or MDS based on the extent of the infection and the sub category of the disease. In addition, the age of the patient should also be taken into account along with the status of the health. IPSS (International Prognostic Scoring System)-R score is extremely important to underline the type of the treatment that has to be followed for myelodysplastic syndromes or MDS. It would go a long way in making the option effective in an impeccable manner.

Apart from the main process, treatment of symptoms and the side effects for myelodysplastic syndromes or MDS are also taken into account. Patient should communicate with the doctors to understand the scope of the remedies. In addition, one should also discuss the objectives of the treatment with the doctors.

  1. Chemotherapy for Myelodysplastic Syndromes or MDS

    Chemotherapy can be helpful in treating myelodysplastic syndromes or MDS. Chemotherapy is a process that helps to eliminate the unhealthy cells in an impeccable manner. Generally, the cells lose the capability to multiply and divide. It is a treatment procedure that should be carried under the jurisdiction of oncologist. Hematologist plays an important role in treating the symptoms of blood disorders.

    Systemic chemotherapy for myelodysplastic syndromes or MDS comprises of the fusion of the drugs into the blood stream using the Intravenous tube with the needle. In addition, one can also consume the pills orally.

    Patients undergoing chemotherapy for myelodysplastic syndromes or MDS are treated in different cycles over fixed time duration. Single or combination of the drugs is used to treat the patients. Some of the drugs for myelodysplastic syndromes or MDS are as follows:

    • Decitabine or Dacogen
    • Idarubicin or Idamycin
    • Lenalidomide or Revlimid
    • Azacitidine or Vidaza
    • Cytarabine or Cytosar-U
    • Daunorubicin or Cerubidine.

    People who are exposed to higher risk of diseases can easily benefit from the treatment of chemotherapy. Cytarabine along with Idarubicin works in combination to provide effective medication to the users. Myelodysplastic syndromes or MDS if left untreated can get transformed into AML or Acute myeloid leukemia. More than 30% of the patients of myelodysplastic syndromes or MDS recover from the disease due to chemotherapy. In addition age of the patient should be taken into account.

    Lenalidomide is consumed orally by the patients with a lower risk of myelodysplastic syndromes or MDS and are affected by the abnormalities in the chromosome. Doctors have to find the issue related to genetic problems.

    Decitabine along with Azactidine are used in treating the myelodysplastic syndromes or MDS disease because they are authenticated by the FDA (Food and Drug Administration). Generally, doctors use them for the patients with extremely high IPSS (International Prognostic Scoring System)-R scores. The medicine can be administered either at the doctor's clinic or at the home of the patients.

    Some of the aide effects of chemotherapy for myelodysplastic syndromes or MDS include extreme fatigue, diarrhea along with nausea and the hair loss. In addition, the patient may also suffer from the loss of appetite. After the treatment is completed, the side effects are eliminated.

    Patient should learn the intricate details of chemotherapy and how it would benefits the health. Medications for the myelodysplastic syndromes or MDS are continually evolving with the advancement in research. You can ask thee physicians about the benefits and the side effects of the chemotherapy treatment in detail.

  2. Immunotherapy for Treating Myelodysplastic Syndromes or MDS

    Immunotherapy is also a viable treatment for myelodysplastic syndromes or MDS. Immunotherapy is concerned with the boosting of the immune system of the body to resist the onset of myelodysplastic syndromes or MDS. The cells of the body are used to make the resistance mechanism strong and durable. anti-thymocyte globulin (Thymoglobulin, ATGAM) medication is used for the therapy and goes a long way in delivering sterling results to the users. By consuming the medication, the immune functions of the body of the victims of myelodysplastic syndromes or MDS can be improved by many notches.

  3. Stem Cell Transplantation/Bone Marrow Transplantation for Treating Myelodysplastic Syndromes or MDS

    Stem cell transplantation/bone marrow transplantation can be used effectively for treating myelodysplastic syndromes or MDS. Chemotherapy along with stem cell transplantation is used to provide relief to the patients of myelodysplastic syndromes or MDS in an impeccable manner. The treatment option plays a very important role in reducing the rate of spread of disease. Bone marrow transplant is successful however its long term effectiveness is in doubt and requires advanced consultation with the doctors specialized in myelodysplastic syndromes or MDS. Patients of myelodysplastic syndromes or MDS with more than 50 years of age can opt for ALLO transplant. Prior to opting for the treatment, the patient should discuss the risk factors with the doctors. Generally, the option is based on the age and health of the individual.

    In stem cell therapy for myelodysplastic syndromes or MDS, the bone marrow is removed and is replaced with the hematopoietic stem cells that can recreate healthy bone marrow after a period of time. The cells can be easily found in the blood stream. It is called stem cell transplant because they are used to generate the bone marrow cells.

    ALLOGENIC transplants are performed with the help of the stem cells donated from healthy people while the AUTO transplant uses the stem cells of the same patient. The primary motive of the doctor is to eliminate the unhealthy cells from the body in an easy and hassle free manner. Sometimes in myelodysplastic syndromes or MDS, chemotherapy is used to destroy the defective cells and new ones are generated with the help of the stem cell therapy. ALLO transplant is more popular for the people affected with myelodysplastic syndromes or MDS.

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Written, Edited or Reviewed By:

, MD, FFARCSI

Last Modified On: May 19, 2016

Pain Assist Inc.

Pramod Kerkar
  Note: Information provided is not a substitute for physician, hospital or any form of medical care. Examination and Investigation is necessary for correct diagnosis.

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