This medicine kcentra is made with the help of pooled plasma of donors who are really healthy which helps in reducing the chances of transmitting any diseases. Kcentra is approved by FDA which was based on a study on 216 patients who used the medicine for the treatment of acute major bleeding. Kcentra is used for quick results when compared to plasma due to its ability to stop acute major bleeding.
How Effective is Kcentra?
The Kcentra (prothromobin complex concentrate, human) is approved by the US Food and Drug Administration for effective use as an urgent reversal of VKA (Vitamin K Anticoagulation) mainly in adults who are suffering from acute major bleeding. The only other treatment for this that is approved in the United States is Plasma.
All patients who are given VLA anticoagulants and chronic anticoagulation therapy with warfarin to prevent and treat blood clotting mainly in those with medical conditions such as atrial fibrillation or when the heart valve has bleeding disorders. Kcentra is mainly used to effectively stop bleeding as it is used in conjunction with the vitamin K which then reverses anticoagulation similar to plasma. However main difference is that plasma required blood group typing and is not needed in case of Kcentra.
Kcentra is mainly related with the occurrence of blood clots when it is used as doctors indicate as it carries a risk regarding blood clots. The medicine kcentra comes with warnings that make it important to check the patient regularly for thromboembolic events as non-fatal and fatal arterial and venous thromboembolic symptoms and conditions have been found in trials in clinics.
What are the Side Effects of Kcentra?
This applies to prothrombin complex: This is an intravenous powder for solution.
Apart from the main effects of kcentra there could also be some additional affects that are caused by prothrombin complex which is the main and active ingredient of kcentra. Therefore, if any of these side effects occur, you need to get immediate medical assistance.
If you experience any of these side effects taking kcentra you must call your doctor or nurse for immediate assistance.
Less common side effects of kcentra:
- Increased thirst
- Pounding in the ears
- Chest pain
- Troubled breathing
- Weight gain
- Loss of appetite
- Blurred vision
- Dry mouth
- Troubled breathing at rest
- Slow or fast heartbeat
- Irregular heartbeat
- Tightness in the chest
- Unusual tiredness or weakness
- Decrease in the amount of urine
- Pounding, fast, or irregular heartbeat or pulse
- Sudden, headache, severe
- Rattling breathing, noisy
- Tingling or numbness in the hands, lips, feet
- Cramps or muscle pain
- Swelling of the hands, fingers, lower legs, feet
- Vomiting or nausea
- Faintness, lightheadedness, dizziness when getting up suddenly from a lying or sitting position.
Minor Side Effects of Kcentra
Most of the side effects that occur while on kcentra do not need medical help. Just as the body begins to cope with the medicine kcentra they will disappear. Your doctor will also help you in advising ways to reduce these side effects. In case these side effects of kcentra continue and reoccur in that case, you must talk to your doctor immediately and get appropriate treatment for it.
More common minor side effects of kcentra:
- Joint pain
- Stiffness or muscle pain
- Difficulty with moving
Less common minor side effects of kcentra:
- Tearing of skin
- Trouble speaking
- Difficulty having a bowel movement.
Unknown Kcentra Incidence:
Coldness, ulceration, Bleeding, tenderness, redness, hives, itching, tingling, discoloration of the skin, numbness, blistering, swelling, lumps, inflammation, scarring, stinging, infection, feeling of pressure, burning, soreness, rash, pain.