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Quercetin and Endurance Training : An Unconventional Approach to Enhancing Athletic Performance

Quercetin, a naturally occurring flavonoid found in a variety of fruits, vegetables, and grains, has garnered increasing interest in the world of sports nutrition for its potential to enhance athletic performance. This antioxidant powerhouse is being recognized for its role in endurance training and the subsequent unconventional approach to boosting athletic capability.

Quercetin & Endurance Training: An Emerging Symbiosis:

Traditionally associated with its antioxidant properties, Quercetin offers a wide array of health benefits ranging from anti-inflammatory effects to potential cancer prevention. Recently, its potential influence on endurance training has entered the scientific spotlight. Research suggests that Quercetin could have a positive impact on athletic performance by increasing mitochondrial biogenesis – the process responsible for producing powerhouses in our cells that generate energy, thus enhancing endurance.

The Science Behind It:

A study published in the “International Journal of Sports Nutrition and Exercise Metabolism” explored the effects of Quercetin on endurance capacity and maximal oxygen capacity (VO2 max) in healthy, physically fit men. Participants supplemented with Quercetin showcased a significant increase in endurance exercise capacity compared to a placebo group, highlighting Quercetin’s potential role in improving athletic performance.

In another double-blind, randomized control trial featured in “Journal of Applied Physiology,” a two-week supplementation of Quercetin resulted in a notable increase in cycling time to fatigue and mitochondrial DNA, further emphasizing its beneficial role in endurance training.

Quercetin Supplementation & Athletic Performance:

While the typical diet can provide some amount of Quercetin, athletes aiming for enhanced performance might require supplementation. It is generally recommended to take 500-1000 mg of Quercetin daily, preferably in divided doses, to support endurance training. However, the exact dosage may vary based on individual factors such as body weight, metabolic rate, and training intensity. Athletes are advised to consult with a healthcare professional or a sports dietitian to optimize the use of Quercetin.

Potential Side Effects and Considerations:

Like any supplement, Quercetin may have potential side effects such as headaches, stomach upset, or tingling sensation. However, these side effects are generally rare and occur with high dosage. As with all dietary supplements, it’s crucial to choose high-quality, third-party tested products to ensure safety and efficacy.


The potential of Quercetin to enhance athletic performance, particularly in endurance training, presents an exciting frontier in sports nutrition. As athletes and trainers continue to seek natural, safe, and effective methods to enhance performance, the role of Quercetin seems poised for further exploration. Though more research is needed to solidify these findings and establish comprehensive usage guidelines, Quercetin’s potential cannot be understated.


  1. Davis JM, Carlstedt CJ, Chen S, Carmichael MD, Murphy EA. The dietary flavonoid quercetin increases VO(2max) and endurance capacity. Int J Sport Nutr Exerc Metab. 2010 Feb;20(1):56-62.
  2. Davis JM, Murphy EA, Carmichael MD, Davis B. Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance. Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1071-7.
Team PainAssist
Team PainAssist
Written, Edited or Reviewed By: Team PainAssist, Pain Assist Inc. This article does not provide medical advice. See disclaimer
Last Modified On:August 1, 2023

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