Effectiveness of Excedrin & Its Side Effects

You should not give Excedrin to teenagers or children with chicken pox, flu or fever symptoms. This is because Aspirin can help origin reye’s syndrome which is a fatal and serious illness in children.

You should not take excess dose of Excedrin than recommended. Large amounts of acetaminophen (within excedrin) can cause death or damage your liver. You should contact your doctor immediately if you have upper stomach pains, itching, dark urine, yellowing of eyes or skin, or clay colored stools.

How Does Excedrin Work?

Excedrin is made up of aspirin, acetaminophen and caffeine. Acetaminophen reduces fever and relieves pain. Aspirin is grouped under salicylates drugs. It reduces substances that cause fever, pain and inflammation in the body. Caffeine is used to stimulate the central nervous system. It contracts and relaxes blood vessels to promote blood flow.

How Effective is Excedrin?

How Effective is Excedrin?

Excedrin is effectively used in treatment of pain caused by migraine headaches, menstrual cramps, muscle aches, tension headaches, toothaches, arthritis, nasal congestion or common cold.

Aspirin can also cause fatal stomach intestinal bleeding. Call your doctor immediately if you have symptoms like tarry or bloody stools, or vomiting and coughing of blood that looks like coffee grounds.

Acetaminophen may cause severe skin reactions in rare cases. Stop using Excedrin at once and inform your doctor right away if you have a rash that spreads and causes peeling or blistering or skin redness.

Do not Use Excedrin In the following Cases:

Do not use excedrin if you are allergic to aspirin, acetaminoohen (tylenol), caffeine or any NSAIDs such as motrin, advil, orudis, aleve, lodine, indocin, toradol, voltaren, relafen, mobic, feldene among others.

Aspirin can cause fatal intestinal or stomach bleeding. These conditions may manifest without warning when using Excedrin.

You should ask your doctor or pharmacist if it is safe to use excedrin when having conditions such as;

Seek medical attention when you use Excedrin to diagnose headache while having:

  • A bad headache that you need to lie flat on surface;
  • A headache resulting vomiting;
  • The worst headache that you’ve ever had;
  • A headache that appears different from your usual headaches;
  • Daily headaches
  • Headache after bending, coughing, head injury or exercising
  • If any doctor diagnosed you for migraines or
  • If you have your first headache after 50 years of age.

Can Pregnant Women Take Excedrin?

The use of excedrin while being pregnant can cause damage to unborn baby’s heart. Acetaminophen, aspirin and caffeine which is contained in excedrin can get mixed with breast milk which would harm baby. This is why women should not breast feed while taking this medicine. Do not breastfeed while taking Excedrin. Caffeine, Acetaminophen, and Aspirin may pass to breast milk and harm your child.

What are the Side Effects of Excedrin?

Common side effects of excedrin Includes:

  • Heartburn, stomach upsets are side effects of excedrin.
  • Restlessness, anxious feeling, depressed mood, or
  • Sleep problems (insomnia).

Seek emergency medical help if you experience allergic reactions to Excedrin, such as breathing difficulty, hives, swelling of your tongue, lips, face or throat.

Acetaminophen can cause fatal skin reactions in rare cases. This can happen even if you took Acetaminophen before and had no reactions. Stop using Excedrin at once and call your doctor of you experience a rash that spreads and causes peeling and blistering or skin redness. You should never again use medicines that contain Acetaminophen if you have such reactions.

Stop taking excedrin and inform your doctor immediately if you have the following severe side effects of excedrin:

  • Severe agitation, anxiety, panic, confusion,
  • Easy bleeding or bruising,
  • A light-headed feeling, like you might pass out;
  • Hot or thirsty feeling, not able to urinate, dry or hot skin and heavy sweating:
  • Signs of stomach bleeding such as tarry or bloody stools and coughing or vomiting blood;
  • High potassium- muscle weakness, slow heart rate, tingly feeling;
  • Liver problems- upper stomach pain, nausea, itching, dark urine, loss of appetite, clay-colored stools, jaundice (yellowing of eyes or skin).

Can I take Other Drugs Along With Excedrin?

There are other drugs that can interact with Excedrin includes prescriptions and over the counter medications, herbal products and medicines. Inform your doctor about all the medicines you are taking or medicines you stopped or started using.

Pramod Kerkar, M.D., FFARCSI, DA
Pramod Kerkar, M.D., FFARCSI, DA
Written, Edited or Reviewed By: Pramod Kerkar, M.D., FFARCSI, DA Pain Assist Inc. This article does not provide medical advice. See disclaimer
Last Modified On:July 27, 2017

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