How Effective is Kazano & What are its Side Effects?

Kazano medicine can cause a serious health condition also known as lactic acidosis. Even if you get any of these symptoms get immediate medical assistance: Cold or numb feeling in legs or arms, weakness or muscle pain, uneven or fast heart rate, difficulty in breathing, dizziness, stomach pain, feeling tired or very weak.

How Effective is Kazano?

How Effective is Kazano?

Kazano has two main composition combination, metformin and alogliptin. Both these are effective oral medicines for diabetes that helps to maintain and control blood sugar levels in the body

The main role of metformin is to effectively decrease the glucose level (sugar production) in the liver. It also works on decreasing glucose absorption by the intestines. Alogliptin is responsible for the regulation of insulin levels produced by body after food consumption.

Kazano is used along with proper exercise and diet to maintain blood sugar levels mainly in adults suffering from type 2 diabetes.

Kazano medicine is not used for the treatment of type 1 diabetes.

Vital Details

This medicine kazano is not to be used if you are suffering from diabetic ketoacidosis or kidney disease. If you are having any of these get immediate doctors help.

Alogliptin (a composition of kazano) can also cause pancreatitis. You will need to stop using this medicine if you have vomiting or nausea, severe pain in upper stomach that later spreads towards your back and loss of appetite.

Prior to Taking Kazano

Do not take kazano if you are allergic to metformin or alogliptin or if you are suffering from:

  • Diabetic ketoacidosis (contact your physician to treat your condition with insulin)
  • Severe kidney disease

There are chances for some people to develop a serious medical condition known as lactic acidosis while taking kazano. The chances of this increases if you are have congestive heart failure, kidney disease, too much alcohol consumption or if you are frequently dehydrated. You must talk about your physician about risk of kazano.

You must tell your doctor if you have any of these medical conditions to make sure kazano is safe for you

  • Liver disease
  • Kidney disease
  • Gallstones
  • History of pancreatitis

If you are over 80 years of age and have not had your kidney functions tested recently

  • History of alcoholism
  • Heart disease

You will have to stop taking kazano for a short period if you have to take an x-ray or any CT scan which will need you to inject a dye to your vein. It is important for your family or caretakers to know about your condition, medicines you are taking and its risks as well.

There are a few oral medications for diabetes which might increase the chances of heart problems. Also, if you are not treating your diabetes in time it can also damage several organs and even heart organs.

If you are breast feeding a baby or pregnant while taking kazano, you must carefully listen to your doctor’s advice correctly. It is very important to maintain your blood sugar levels at the time of pregnancy, and the dosages you take might have to be changed during every trimester. Similarly, dosage levels might also require maybe different when you are breast feeding your child.

There are possibilities of kazano for the stimulation of ovulation in women with premenopausal. Also, it can also increase the risk of unplanned pregnancy. Therefore, you must talk to your doctor about all the risks of taking this medicine.

It is important to inform your doctor if you are breast feeding your child as it is unknown if this medicine can pass through breast milk to the child.
Kazano should not be given to anyone below 18 years of age.

What is the Recommended Dosage of Kazano?

Kazano – Treatment for Diabetes Type 2 – Regular Adult Dosage

The first dosage has to be depending on the current treatment required for the patient

First dosage: Metformin 500 milligrams-alogliptin 12.5 milligrams or metformin 1000 milligrams-alogliptin 12.5 milligrams two time a day orally

Maintenance dosage: The dosage can be changed mainly based on the tolerability and efficacy of the patient

Maximum dosage: metformin 2000 milligrams-alogliptin 25 milligrams per day

If kazano is used along with insulin or insulin secretagogues like sulfonylureas, you need to take only a small dosage of insulin secretagogues or insulin in order to prevent the risk of getting hypoglycemia.

The dosage level of metformin (a composition of kazano) must be slowly titrated and must be taken with food in order to lower the risk of gastrointestinal side effects.

What are the Side Effects of Kazano?

If you experience any symptoms of pancreatitis, get immediate medical assistance. Signs are vomiting and nausea, rapid heartbeats, severe pain in upper stomach that gradually spreads to your back, loss of appetite.

There are possibilities for some people taking kazano to develop a serious medical condition, lactic acidosis. Starting symptoms might get worse in time and cause a very severe fatal condition. Therefore, if you experience any of these symptoms, stop taking this medicine and get immediate medical assistance

  • Trouble breathing
  • Uneven or slow heart rate
  • Light headed, dizziness feeling, weak, tired
  • Cold or numb feeling in your legs and arms
  • Weakness or muscle pain
  • Nausea with vomiting or Stomach pain

Also, get immediate medical assistance if you experience any of these below severe side effects of kazano:

  • Burning or pain when you urinate
  • Ongoing or severe pain in joints
  • Liver problems: tired feeling, dark urine, upper stomach pain, nausea, clay colored stools, itching, jaundice (yellowing of eyes or skin), nausea
  • Heart problems: rapid weight gain, swelling in your legs or feet or midsection, shortness of breath mainly while lying down
  • Serious skin reaction: burning in your eyes, purple or red skin rashes which spreads to mainly upper body and face causing peeling and blistering, swelling in your tongue or face, sore throat, fever

Here are the other common side effects of kazano:

  • Upset stomach, diarrhea
  • Headache, back pain
  • High blood pressure (blurred vision, severe headache, pounding in ears or neck)
  • Cold symptoms like sinus pain, stuffy nose, sore throat are also side effects of kazano.
Pramod Kerkar, M.D., FFARCSI, DA
Pramod Kerkar, M.D., FFARCSI, DA
Written, Edited or Reviewed By: Pramod Kerkar, M.D., FFARCSI, DA Pain Assist Inc. This article does not provide medical advice. See disclaimer
Last Modified On:June 10, 2019

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